In SLO CAL (San Luis Obispo County), a weekend getaway feels easy by design. Here miles turn into minutes, scenic drives connect coastal towns with inland valleys and each community brings its own unique rhythm, SLO CAL is the perfect region to bring your girls for a fun-filled escape. Whether your group gravitates toward the coast, wellness rituals, outdoor adventure, food-driven tours or wine tasting days, the region offers space to slow down and enjoy time together. 

Here are five SLO CAL girls weekend trip itineraries that invite you to experience a little bit of everything the region has to offer! 

Beach and Coastal Girls Getaway

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Three women running from the sauna to the bay with Morro Rock in the background

There's a reason SLO CAL comes to mind when dreaming of the perfect ocean escape. With more than 80 miles of coastline, this itinerary is made for friend groups who love salty air, sunset walks and days shaped by the tides. 

 

Day 1 

Start off the weekend by checking into an oceanside hotel or vacation rental. The region's coastal cities are filled with charming accommodations that offer exciting experiences depending on your group’s needs. Consider booking a room at The Cliffs Hotel and Spa in Pismo Beach, an ocean front retreat perched on a bluff with sweeping views and convenient access to a spa and pool. 

After settling into your rooms, spend the afternoon exploring neighboring Avila Beach. Stroll along the shoreline and pop into local shops. A scoop (or two) from Reimer’s Ice cream adds a sweet treat before heading back to Pismo Beach for dinner at Oyster Loft, a refined seafood restaurant known for their fresh fish and warm atmosphere. End the evening with a sunset stroll along the Pismo Beach pier

 

Day 2 

Start the morning with a drive north on Highway 1 and grab some coffee and bites at Cambria Coffee Company before taking a stroll down one of Cambria’s most scenic spots, Moonstone Beach. Keep an eye out for the smooth, colorful stones along the coast. Before embarking on the next adventure, take your group to fuel up with brunch at Creekside Gardens Cafe. Afterwards, make your way to Morro Bay for paddleboarding or kayaking with A Kayak Shack. They offer single paddleboards and kayaks for the solo adventurers or tandem kayaks for the girls that prefer to paddle together! 

As the day winds down, wander the Morro Bay embarcadero shops and waterfront paths, where local art and coastal charm meet. End the night with a laid-back dinner at Umi Sushi, steps from the water. For those wanting to keep the night going, drive right onto Pismo State Beach for a cozy bonfire, perfect for s’mores, stargazing, deep chats and winding down together. 

 

Day 3 

Before your coastal getaway comes to an end, enjoy breakfast or brunch at HolyBelly in Grover Beach, a spot blending Mexican flavors with American breakfast. Then make one last stop at Spyglass Beach Tide Pools to take in the spectacular ocean views and array of marine life! At low tide, tide pools are uncovered to reveal underwater ecosystems. Look closely and you may be able to spot anemones, starfish, crabs and more. 

Wellness and Self-Care Girls Retreat

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person getting a massage at a spa

For groups looking to slow things down and truly unwind, a wellness-focused weekend in SLO CAL is the perfect reset. From scenic drives to mineral springs and spa days, this itinerary is all about intentional moments, fresh air and leaving feeling refreshed. 

 

Day 1 

Begin your wellness weekend by checking into a boutique hotel like Petit Soleil in the city of San Luis Obispo. This charming stay offers an intimate and peaceful atmosphere that sets the tone for a restorative getaway. After dropping off your bags, take the scenic Prefumo Canyon Road toward Avila Beach. This is the perfect time to roll the windows down and turn up the tunes while taking in the scenery of the rolling hills and trees. 

Once in Avila Beach, stroll along the Harford Pier and enjoy the ocean breeze. In the evening, head to Sycamore Mineral Springs for a relaxing soak in their naturally heated mineral tubs tucked into the hillside. End the day back in downtown San Luis Obispo at Mistura, where comforting dishes and an elegant ambiance makes for the ideal dinner with the girls. 

 

Day 2 

Start the morning with movement at a group yoga class at Harmony House Yoga in Pismo Beach. After class, refuel with a healthy and nourishing bowl from Y’Not Organic before making your way north to Atascadero. Spend the afternoon indulging in spa treatments at Heart and Soles Day Spa to relax your bodies and minds, followed by a peaceful walk through Three Bridges Oak Preserve. This quiet nature space offers shaded trails and open scenery, perfect for unwinding between activities. For dinner, head to Cielo Restaurant and Rooftop Bar in Atascadero, featuring an upscale Italian dining experience. If the group is looking for a relaxed evening drink, head upstairs for a rooftop bar setting with amazing views of the surrounding scenery. 

 

Day 3 

On the final morning of this memorable girls trip, make your way north along Highway 1 to Hidden Kitchen in Cayucos for breakfast. Grab a table outside and enjoy their famous blue corn waffles. Whether your group enjoys savory flavors or sweet toppings, Hidden Kitchen has the best of both worlds! Before heading home, book a group sauna and cold-water immersion session with California Sauna Club in Morro Bay for a grounding finish to your weekend.

Adventure-Filled Girls Trip

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couple zip-lining over trees

Does your gal group thrive on movement and memorable experiences? This adventure-filled itinerary blends high-energy activities with classic SLO CAL scenery. 

 

Day 1 

Arrive to SLO CAL ready to explore. If you are looking for a vacation rental suited to accommodate groups and inspire an outdoorsy spirit, check out Hacienda Felise Estate and Inn or book The Big House, both conveniently located in Arroyo Grande. Once settled, head to Oceano Dunes State Vehicular Recreation Area for an evening of off-road exploration. Don’t have your own off-roading vehicle? Sunbuggy Fun Rentals offers ATV, UTV and dune buggy rentals and tours, making it easy to jump right in. End the day with dinner and drinks at Lure Fish House in San Luis Obispo. 

 

Day 2 

Start the morning early with a sunrise hot air ballon ride with Ballons Over Paso. Floating above vineyards and rolling hills offers a once-in-a-lifetime perspective and sets the tone for an unforgettable day. After landing, enjoy breakfast at Cowgirl Cafe in Paso Robles before heading south to Santa Margarita for a guided horseback ride with Central Coast Trailrides. Partnering with local vineyards and wineries, private ranches and The Land Conservatory of San Luis Obispo, Central Coast Trailrides is a unique opportunity to see SLO CAL’s picturesque landscape on horseback. Alternatively, if you want to explore the scenery around the iconic Madonna Inn, Madonna Inn Trail Rides is a great option for both novice and skilled riders. 

Stop for lunch at Kula Hawaiian Kitchen in Atascadero or explore local eateries in San Luis Obispo, then spend the afternoon testing your balance and bravery at Vista Lago Adventure Park in Arroyo Grande. End the day back near the coast with dinner at Umi Sushi Pacifica in Grover Beach, where creative rolls and fresh flavors make for a relaxing evening. 

 

Day 3 

Ease into your final morning with coffee from Kraken Coffee in Avila Beach. Head north to Morro Bay for kayaking or paddleboarding, taking in views of Morro Rock and the surrounding estuary. Afterwards, enjoy brunch at High Street Deli in Los Osos before squeezing in one last outdoor adventure. Choose between a hike or mountain bike ride to explore coastal trails and sweeping views at Montana de Oro State Park before heading home. 

Sip and Stay Girls Getaway

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Two ladies wine tasting at Booker Winery in Paso Robles

A wine-focused girls weekend in SLO CAL is all about relaxed mornings, scenic vineyard views and tasteful meals. With two distinct wine regions to explore, this itinerary offers the perfect balance of tasting experiences and down time. 

 

Day 1 

Arrive in Paso Robles and check into a stay like Hotel Cheval or Allegretto Vineyard Resort. Booth properties offer proximity to downtown and the tranquil vineyard surroundings—there's no need for your group to choose. Spend the afternoon exploring downtown Paso Robles with a casual tasting room crawl, stopping at LXV Tasting RoomJUSTIN and Serial Wines. As evening approaches, enjoy dinner at Les Petites Canailles, where French-inspired dishes and a warm atmosphere set the mood for a relaxed night out with the girls. 

 

Day 2 

Start the morning with breakfast downtown before heading out for a day of winery hopping. Choose two to three wineries to visit, such as Cass Winery, Niner Estates and Halter Ranch Winery, each offering a unique setting and tasting experience. Many wineries offer lunch options, but if you are craving a bit of everything, stop by Taste! Craft Eatery for a casual bite where everyone can craft their ideal "girl lunch."

Return to your hotel in the afternoon to unwind, lounge by the pool, take a nap or get ready for dinner. In the evening, head back downtown for dinner at Il Cortile Ristorante, known for its refined Italian dishes and intimate ambiance. 

 

Day 3 

On your final day, head south to Edna Valley. Consider visiting Chamisal Vineyards or Biddle Ranch Vineyard, where rolling hills and cool-climate wines create a beautiful setting to close out the weekend. Before heading home, enjoy lunch and a final stroll through The Village of Arroyo Grande, stopping at Mason Bar and Kitchen for a farm-fresh meal and lively atmosphere. 

Foodie-Focused Girls Trip

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Plates of seafood and cocktails at Mitsura restaurant

For groups that plan their travel around what’s on the menu, SLO CAL delivers a rich mix of farm-fresh flavors, creative chefs and unforgettable dining experiences. 

 

Day 1 

Check into a stay that puts you in the center of SLO CAL’s food destinations, such as the luxurious Hotel San Luis Obispo. Right outside the steps of Hotel SLO is Downtown San Luis Obispo where you can browse boutiques, grab a drink and soak in the walkable charm before heading out for dinner. Enjoy an evening meal at Ember in Arroyo Grande, a farm-to-table restaurant known for its seasonal menus and wood-fired cooking sourced from local farms. 

 

Day 2 

Head north to Paso Robles to explore Tin City, a hub for artisan food, wine and craft beverages. Reserve a spot at Six Test Kitchen for an intimate chef’s counter experience featuring a multi-course tasting menu, or stop by Etto Pasta Bar for freshly made pasta and bold flavors. Balance out the day with a visit to BarrelHouse Brewing Co. for craft beers and a laid-back atmosphere. 

Return to San Luis Obispo for dinner at Sushi Table, a speakeasy style sushi bar offering a 16-course omakase experience. Cap off the night with drinks at Feral, a downtown cocktail bar known for its creative menu and cozy setting. 

 

Day 3 

Enjoy breakfast at Lido Restaurant in Pismo Beach before taking a scenic drive up Highway 1. Be sure to stop to explore the coastal trails at Fiscalini Ranch Preserve in Cambria, where ocean views and open space provide the perfect pre-lunch stroll. Finish the weekend with lunch at Robin’s restaurant, a longtime Cambria favorite known for its globally inspired comfort food. 

No matter how your group loves to travel, a girls weekend in SLO CAL offers the freedom to make it your own. From coastal mornings and wellness rituals, to vineyard afternoons, adrenaline-filled adventures and unforgettable meals, each itinerary highlights a different way to experience the region. However you choose to spend your days, SLO CAL sets the scene for memories that last longer than the weekend stays. Plan your girls weekend today!